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The Best cardiac rehab website

All the cardiac rehab information you need to know about is right here. Presented and researched by http://www.medical-mailings.com. We've searched the information super highway far and wide to provide you with the best cardiac rehab site on the internet today. The links below will assist you in your efforts to find the information that you are looking for about
cardiac rehab.

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Need information on Medical Mailings? Our links will provide you with information on all type of type of Medical Mailings for Physicians over the internet including email and snail mail. For conferencing services to go with your email campagin go to Meetings on the Net - http://www.meetingsonthenet.com
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While the threat from hackers is low for individuals, a more serious threat to personal privacy comes from unscrupulous cardiac rehab companies that operate websites for quick quids. Many cardiac rehab sites require you to register before you can use its services. Often you must provide personal information, such as your name, street address, and e-mail address. Then as you browse the site, data is collected as to which pages you visited, how long you remained on each page, the links you clicked, what terms you searched, and so on. After a number of visits to the site, a personal profile emerges. The question is, what do cardiac rehab site operators do with this information?

Most claim that they use it to personalize your experience on the site. For instance, if a cardiac rehab site learns that you are interested in cardiac rehab, the next time you visit the site, you might be presented with an article or advertisements for that and related products. But some cardiac rehab websites sell this information to marketers, which means that you may find yourself receiving unwanted catalogs from garden suppliers. Our preferred retailer does not do this.

cardiac rehab

medical mailings, email campaigns
Need information on Medical Mailings? Our links will provide you with information on all type of type of Medical Mailings for Physicians over the internet including email and snail mail. For conferencing services to go with your email campagin go to Meetings on the Net - http://www.meetingsonthenet.com
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The following link will take you to a great cardiac rehab supplier who can help you with exactly what you need.

Of course if you just can't get enough cardiac rehab information then keep on browsing AFTER you add this page to your favourites. Why?

Because when you finally get sick of browsing through the rubbish for cardiac rehab you'll want to get back here as quickly as possible so you can find the cardiac rehab information you were after in the first place.

So if you are serious about finding great cardiac rehab information, add us to your favourites or click the above link right now.

Glutathione - Your Brain's Master Antioxidant Defense

 by: Priya F Shah

Free radicals and oxyradicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, schizophrenia and Down syndrome.

Glutathione is the brain's master antioxidant and plays an important protective role in the brain.

According to Dr. Jimmy Gutman, "The brain is particularly susceptible to free radical attack because it generates more oxidative by-products per gram of tissue than any other organ."

Many neurological and psychiatric disease processes are characterized by... abnormalities in glutathione metabolism and antioxidant defenses."

Generation of reactive oxygen species (free radicals) and oxidative damage are an important cause of neuron (brain cell) death from brain injury.

Chemicals that cause toxicity to certain brain cells are known to decrease cerebral glutathione (GSH), making the cells more vulnerable to reactive oxygen species (ROS). (1)

On the other hand, over-expression of the glutathione peroxidase (GPX) enzyme potently decreases cell death from brain injury. (2)

Brain Injury and Glutathione - The Gender Difference

Researchers at Children's Hospital of Pittsburgh have found that males and females respond differently to brain injury. (3)

In animal models, levels of glutathione remain constant in females who have suffered a brain injury, but drop by as much as 80 percent in males with the same injury.

When glutathione levels drop, brain cells die much more quickly. This suggests that boys with brain injuries may require different life-saving treatments than girls.

N-acetyl-cysteine (NAC), a precursor of glutathione, already approved for use by the U.S. Food and Drug Administration to treat people who have overdosed on acetaminophen, may be an effective treatment for brain injury in boys whose brains are deprived of oxygen.

Brain Disorders and Glutathione - A Genetic Cause?

Genetics researchers have found that the glutathione S-transferase gene controls the onset of Alzheimer's, Parkinson's disease and determines, not if we get these diseases, but when. (4)

The glutathione S-transferase gene has previously been linked to the risk for Parkinson's disease among people who used pesticides.

A previous article covered the importance of glutathione in Parkinson's Disease.

http://www.1whey2health.com/parkinsons_glutathione.htm

Alzheimer's Disease and Glutathione

Free radicals and oxidative damage in neurons is known to be a primary cause of degenerative diseases like Alzheimer's disease.

Amyloid-ß peptide (Aß) accumulation in senile plaques, a pathological hallmark of Alzheimer's disease (AD), has been implicated in neuronal degeneration.

Amyloid plaques encroaching on the brain increase the production of free radicals, or oxidative stress. Antioxidants, such as vitamin C and E "mop up" the damaging free radicals.

Glutathione (GSH) precursors can prevent death of brain cells induced by amyloid plaques in Alzhiemer's disease, while substances that deplete GSH increase cell death. (5)

Evidence has been piling up over the link between the amount of an amino acid called homocysteine in the blood and the chance of developing Alzheimer's.

For people not genetically predisposed to developing Alzheimer's, cholesterol and homocysteine, largely caused by an unhealthy lifestyle, are the core causal factors.

Welsh GP, Andrew McCaddon, showed that the more homocysteine that patients with Alzheimer's had, the worse their mental performance, and the worse their "cognitive impairment," the less they had of the antioxidant glutathione. (6)

Glutathione and Mood Disorders

Studies have found that the mood stabilizing drug, valproate, used to treat epilepsy and bi-polar disorder, regulates expression of the genes that make glutathione-S-transferase (GST).

In addition, chronic treatment with lithium, another commonly prescribed mood stabilizer used in treating manic-depression, also increased levels of GST.

These findings led researchers to conclude that glutathione S-transferase may be a novel target for mood stabilizing drugs. (7)

Alcohol Consumption and Glutathione

Alcohol abuse is known to impair memory and other brain functions and increase brain cell death. A new study in rats has shown that alchol consumption causes fewer new brain cells to form and results in greater cell death. (8)

But rats that were fed alcohol along with Ebselen - a glutathione peroxidase mimic that acts as a free radical scavenger - showed no similar reduction in brain-cell formation and no increase in cell death.

Substances that Boost Glutathione Levels and Protect Brain Cells

Taking glutathione itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells.

However, intravenous glutathione therapy and glutathione precursors or dietary supplements are effective in boosting intracellular levels of glutathione.

Intravenous Glutathione Injections: Intravenous glutathione injections have been shown to produce amazing and rapid results, in patients with Parkinson's disease. Following even a single dosage of intravenous glutathione, many of the symptoms of Parkinson's disease rapidly improve, often in as little as 15 minutes.

Glutathione Precursors: In the Alzheimer's study conducted by Welsh GP, Andrew McCaddon, adding the glutathione precursor, N-acetyl-cysteine (NAC) to a protocol that lowered homocysteine levels by simple supplementation with B12 and folate, resulted in prompt, striking, and sustained clinical improvement in nearly all the patients. (9)

Cucurmin (turmeric): Studies have shown that the Indian curry spice, cucurmin, has neuroprotective effects because of its ability to induce the enzyme, hemeoxygenase-1 (HO-1), which protects neurons exposed to oxidant stress. Treatment of brain cells called astrocytes, with curcumin, increases expression of HO-1 protein as well as glutathione S-transferase. (10)

Ebselen: Ebselen is a glutathione peroxidase mimic and potent synthetic antioxidant that acts as a neuroprotective agent and an inhibitor of free-radical induced apoptosis (cell death). It can protect brain cells from the neuro-toxic effects of alcohol consumption. (8)

Undenatured Whey Protein: Undenatured whey protein provides glutathione precursors, has been shown to raise intracellular glutathione levels in clinical trials, and has anecdotally been reported to improve the symptoms of Parkinson's disease.

References:

1. Journal of Neurochemistry, Vol. 88, No. 3, 2004 513-531

2. Journal of Neurochemistry, Vol. 87, No. 6, 2003 1527-1534

3. Researchers Find Brain Cells Die Differently in Males and Females; Pediatric Academic Societies Press release; 21-Apr-2004

4. Human Molecular Genetics, 2003, Vol. 12, No. 24 3259-3267

5. The Journal of Cell Biology, Volume 164, Number 1, 123-131; 5 January 2004

6. Biol Psychiatry. 2003 Feb;53(3):254-60

7. Journal of Neurochemistry, Vol. 88, No. 6, 2004 1477-1484

8. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7919-24. Epub 2003 Jun 05.

9. Am J Geriatr Psychiatry. 2003 Mar-Apr;11(2):246-9

10. Can Curry Protect Against Alzheimer's?; American Physiological Society (APS) Press Release; 16-Apr-2004

Copyright © 2004 Priya Shah

About The Author

This article was first published in the May 2004 issue of The Glutathione Report, http://www.glutathione-report.com, a newsletter featuring regular updates on the health benefits of glutathione. Get a Free report on Glutathione in Health and Disease http://www.1whey2health.com

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